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Identification of a Different Agonist-Binding Site and Activation Mechanism of the Human P2Y(1) Receptor
The human P2Y(1) receptor (P2Y(1)R) is a purinergic G-protein-coupled receptor (GPCR) that functions as a receptor for adenosine 5′-diphosphate (ADP). An antagonist of P2Y(1)R might potentially have antithrombotic effects, whereas agonists might serve as antidiabetic agents. On the basis of the anta...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653743/ https://www.ncbi.nlm.nih.gov/pubmed/29062134 http://dx.doi.org/10.1038/s41598-017-14268-1 |