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A chloroquine-induced macrophage-preconditioning strategy for improved nanodelivery
Site-specific localization is critical for improving the therapeutic efficacy and safety of drugs. Nanoparticles have emerged as promising tools for localized drug delivery. However, over 90% of systemically injected nanocarriers typically accumulate in the liver and spleen due to resident macrophag...
Autores principales: | Wolfram, Joy, Nizzero, Sara, Liu, Haoran, Li, Feng, Zhang, Guodong, Li, Zheng, Shen, Haifa, Blanco, Elvin, Ferrari, Mauro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653759/ https://www.ncbi.nlm.nih.gov/pubmed/29062065 http://dx.doi.org/10.1038/s41598-017-14221-2 |
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