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Incorporation of tetanus-epitope into virus-like particles achieves vaccine responses even in older recipients in models of psoriasis, Alzheimer’s and cat allergy

Monoclonal antibodies are widely used to treat non-infectious conditions but are costly. Vaccines could offer a cost-effective alternative but have been limited by sub-optimal T-cell stimulation and/or weak vaccine responses in recipients, for example, in elderly patients. We have previously shown t...

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Detalles Bibliográficos
Autores principales: Zeltins, Andris, West, Jonathan, Zabel, Franziska, El Turabi, Aadil, Balke, Ina, Haas, Stefanie, Maudrich, Melanie, Storni, Federico, Engeroff, Paul, Jennings, Gary T., Kotecha, Abhay, Stuart, David I, Foerster, John, Bachmann, Martin F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653761/
https://www.ncbi.nlm.nih.gov/pubmed/29263885
http://dx.doi.org/10.1038/s41541-017-0030-8