Improved detection of BRAF V600E using allele-specific PCR coupled with external and internal controllers

Although traditional allele-specific PCR (tAS-PCR) is a common screening method for BRAF V600E mutations, its lower amplification specificity and mutation selectivity have limited its clinical applications. We hypothesize that these limitations are associated with the weaker specificities of allele-...

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Detalles Bibliográficos
Autores principales: Yang, Zhao, Zhao, Na, Chen, Dong, Wei, Kun, Su, Ning, Huang, Jun-Fu, Xu, Han-Qing, Duan, Guang-Jie, Fu, Wei-Ling, Huang, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653796/
https://www.ncbi.nlm.nih.gov/pubmed/29061997
http://dx.doi.org/10.1038/s41598-017-14140-2

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