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Endogenous physical regulation of population density in the freshwater protozoan Paramecium caudatum
Studies confirm physical long-range cell-cell communication, most evidently based on electromagnetic fields. Effects concern induction or inhibition of cell growth. Their natural function is unclear. With the protozoan Paramecium caudatum I tested whether the signals regulate cell density and are el...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653844/ https://www.ncbi.nlm.nih.gov/pubmed/29062014 http://dx.doi.org/10.1038/s41598-017-14231-0 |
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author | Fels, Daniel |
author_facet | Fels, Daniel |
author_sort | Fels, Daniel |
collection | PubMed |
description | Studies confirm physical long-range cell-cell communication, most evidently based on electromagnetic fields. Effects concern induction or inhibition of cell growth. Their natural function is unclear. With the protozoan Paramecium caudatum I tested whether the signals regulate cell density and are electromagnetic. Up to 300 cells/mL, cell growth in clones of this study is decreasingly pronounced. Using cuvettes as chemical barriers enabling physical communication I placed 5 indicator cells/mL, the inducer populations, into smaller cuvettes that stand in bigger and contained 50, 100, 200 or 300 cells/mL. Under conditions of total darkness such pairs were mutually exposed for 48 hours. The hypothesis was that indicator cells, too, grow less the more neighbor cells there are. The bigger inducer populations were in the beginning the less they grew. The indicator populations grew accordingly; the more cells they were surrounded by the less they grew. The suppressing neighbors-effect disappeared when inner cuvettes were shielded by graphite known to shield electromagnetic radiation from GHz to PHz, i.e. to absorb energy from microwaves to light. These are the first results demonstrating non-contact physical quorum sensing for cell population density regulation. I assume rules intrinsic to electromagnetic fields interacting with matter and life. |
format | Online Article Text |
id | pubmed-5653844 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-56538442017-11-08 Endogenous physical regulation of population density in the freshwater protozoan Paramecium caudatum Fels, Daniel Sci Rep Article Studies confirm physical long-range cell-cell communication, most evidently based on electromagnetic fields. Effects concern induction or inhibition of cell growth. Their natural function is unclear. With the protozoan Paramecium caudatum I tested whether the signals regulate cell density and are electromagnetic. Up to 300 cells/mL, cell growth in clones of this study is decreasingly pronounced. Using cuvettes as chemical barriers enabling physical communication I placed 5 indicator cells/mL, the inducer populations, into smaller cuvettes that stand in bigger and contained 50, 100, 200 or 300 cells/mL. Under conditions of total darkness such pairs were mutually exposed for 48 hours. The hypothesis was that indicator cells, too, grow less the more neighbor cells there are. The bigger inducer populations were in the beginning the less they grew. The indicator populations grew accordingly; the more cells they were surrounded by the less they grew. The suppressing neighbors-effect disappeared when inner cuvettes were shielded by graphite known to shield electromagnetic radiation from GHz to PHz, i.e. to absorb energy from microwaves to light. These are the first results demonstrating non-contact physical quorum sensing for cell population density regulation. I assume rules intrinsic to electromagnetic fields interacting with matter and life. Nature Publishing Group UK 2017-10-23 /pmc/articles/PMC5653844/ /pubmed/29062014 http://dx.doi.org/10.1038/s41598-017-14231-0 Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Fels, Daniel Endogenous physical regulation of population density in the freshwater protozoan Paramecium caudatum |
title | Endogenous physical regulation of population density in the freshwater protozoan Paramecium caudatum |
title_full | Endogenous physical regulation of population density in the freshwater protozoan Paramecium caudatum |
title_fullStr | Endogenous physical regulation of population density in the freshwater protozoan Paramecium caudatum |
title_full_unstemmed | Endogenous physical regulation of population density in the freshwater protozoan Paramecium caudatum |
title_short | Endogenous physical regulation of population density in the freshwater protozoan Paramecium caudatum |
title_sort | endogenous physical regulation of population density in the freshwater protozoan paramecium caudatum |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653844/ https://www.ncbi.nlm.nih.gov/pubmed/29062014 http://dx.doi.org/10.1038/s41598-017-14231-0 |
work_keys_str_mv | AT felsdaniel endogenousphysicalregulationofpopulationdensityinthefreshwaterprotozoanparameciumcaudatum |