Early-onset and classical forms of type 2 diabetes show impaired expression of genes involved in muscle branched-chain amino acids metabolism

The molecular mechanisms responsible for the pathophysiological traits of type 2 diabetes are incompletely understood. Here we have performed transcriptomic analysis in skeletal muscle, and plasma metabolomics from subjects with classical and early-onset forms of type 2 diabetes (T2D). Focused studi...

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Detalles Bibliográficos
Autores principales: Hernández-Alvarez, María Isabel, Díaz-Ramos, Angels, Berdasco, María, Cobb, Jeff, Planet, Evarist, Cooper, Diane, Pazderska, Agnieszka, Wanic, Krzystof, O’Hanlon, Declan, Gomez, Antonio, de la Ballina, Laura R., Esteller, Manel, Palacin, Manuel, O’Gorman, Donal J., Nolan, John J., Zorzano, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653857/
https://www.ncbi.nlm.nih.gov/pubmed/29062026
http://dx.doi.org/10.1038/s41598-017-14120-6

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