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Physicochemical characterisation, immunogenicity and protective efficacy of a lead streptococcal vaccine: progress towards Phase I trial
Globally, group A streptococcal infections are responsible for over 500,000 deaths per year. A safe vaccine that does not induce autoimmune pathology and that affords coverage for most GAS serotypes is highly desired. We have previously demonstrated that a vaccine based on the conserved M-protein ep...
Autores principales: | Pandey, Manisha, Powell, Jessica, Calcutt, Ainslie, Zaman, Mehfuz, Phillips, Zachary N., Ho, Mei Fong, Batzloff, Michael R., Good, Michael F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653875/ https://www.ncbi.nlm.nih.gov/pubmed/29062085 http://dx.doi.org/10.1038/s41598-017-14157-7 |
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