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YAP/TAZ-mediated activation of serine metabolism and methylation regulation is critical for LKB1-deficient breast cancer progression

The crucial interplay between metabolic remodeling and the epigenetics could contribute to promote cancer progression. A remarkable association within interaction, LKB1 has been reported, suggesting that the expression of key enzymes involving de novo serine synthesis and DNA methyltransferases like...

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Detalles Bibliográficos
Autores principales:	Wu, Qi, Li, Juanjuan, Sun, Si, Chen, Xinyue, Zhang, Hanpu, Li, Bei, Sun, Shengrong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2017
Materias:	Hypotheses
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653917/ https://www.ncbi.nlm.nih.gov/pubmed/28931725 http://dx.doi.org/10.1042/BSR20171072

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