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Successful bridge to recovery in fulminant myocarditis using a biventricular assist device: a case report

BACKGROUND: Fulminant myocarditis is a life-threatening disease, and myocardial damage expands the right ventricle as well as the left ventricle in some cases. There is a mortality rate of over 40% in patients with fulminant myocarditis who need mechanical circulatory support by peripheral venoarter...

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Autores principales: Adachi, Yusuke, Kinoshita, Osamu, Hatano, Masaru, Shintani, Yukako, Naito, Noritsugu, Kimura, Mitsutoshi, Nawata, Kan, Nitta, Daisuke, Maki, Hisataka, Ueda, Kazutaka, Amiya, Eisuke, Takimoto, Eiki, Komuro, Issei, Ono, Minoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654049/
https://www.ncbi.nlm.nih.gov/pubmed/29061186
http://dx.doi.org/10.1186/s13256-017-1466-1
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author Adachi, Yusuke
Kinoshita, Osamu
Hatano, Masaru
Shintani, Yukako
Naito, Noritsugu
Kimura, Mitsutoshi
Nawata, Kan
Nitta, Daisuke
Maki, Hisataka
Ueda, Kazutaka
Amiya, Eisuke
Takimoto, Eiki
Komuro, Issei
Ono, Minoru
author_facet Adachi, Yusuke
Kinoshita, Osamu
Hatano, Masaru
Shintani, Yukako
Naito, Noritsugu
Kimura, Mitsutoshi
Nawata, Kan
Nitta, Daisuke
Maki, Hisataka
Ueda, Kazutaka
Amiya, Eisuke
Takimoto, Eiki
Komuro, Issei
Ono, Minoru
author_sort Adachi, Yusuke
collection PubMed
description BACKGROUND: Fulminant myocarditis is a life-threatening disease, and myocardial damage expands the right ventricle as well as the left ventricle in some cases. There is a mortality rate of over 40% in patients with fulminant myocarditis who need mechanical circulatory support by peripheral venoarterial extracorporeal membrane oxygenation. CASE PRESENTATION: We report a case of a 27-year-old Japanese woman who was successfully bridged to recovery by using a biventricular assist device. She was diagnosed with fulminant myocarditis, and peripheral venoarterial extracorporeal membrane oxygenation was established on the same day. Her left ventricular ejection fraction rapidly decreased from 40% to 5% in 3 days and weaning from venoarterial extracorporeal membrane oxygenation was deemed difficult. Therefore, we performed a ventricular assist device implantation on day 4. A left ventricular assist device was implanted first. However, adequate blood flow did not circulate to the left side of her heart because of right-sided heart failure. Thus, an additional implant of a right ventricular assist device was performed during the operation. Her left ventricular ejection fraction recovered to 50% on day 10. The biventricular assist device was successfully removed on day 14. She has not experienced worsening of biventricular function during her follow-ups for 4 years. CONCLUSIONS: Ventricular assist device therapy should be considered if there is no improvement in cardiac function in patients with fulminant myocarditis regardless of several days of support by venoarterial extracorporeal membrane oxygenation. A right ventricular assist device should always be implemented when necessary because biventricular involvement is not uncommon in fulminant myocarditis. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13256-017-1466-1) contains supplementary material, which is available to authorized users.
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spelling pubmed-56540492017-10-26 Successful bridge to recovery in fulminant myocarditis using a biventricular assist device: a case report Adachi, Yusuke Kinoshita, Osamu Hatano, Masaru Shintani, Yukako Naito, Noritsugu Kimura, Mitsutoshi Nawata, Kan Nitta, Daisuke Maki, Hisataka Ueda, Kazutaka Amiya, Eisuke Takimoto, Eiki Komuro, Issei Ono, Minoru J Med Case Rep Case Report BACKGROUND: Fulminant myocarditis is a life-threatening disease, and myocardial damage expands the right ventricle as well as the left ventricle in some cases. There is a mortality rate of over 40% in patients with fulminant myocarditis who need mechanical circulatory support by peripheral venoarterial extracorporeal membrane oxygenation. CASE PRESENTATION: We report a case of a 27-year-old Japanese woman who was successfully bridged to recovery by using a biventricular assist device. She was diagnosed with fulminant myocarditis, and peripheral venoarterial extracorporeal membrane oxygenation was established on the same day. Her left ventricular ejection fraction rapidly decreased from 40% to 5% in 3 days and weaning from venoarterial extracorporeal membrane oxygenation was deemed difficult. Therefore, we performed a ventricular assist device implantation on day 4. A left ventricular assist device was implanted first. However, adequate blood flow did not circulate to the left side of her heart because of right-sided heart failure. Thus, an additional implant of a right ventricular assist device was performed during the operation. Her left ventricular ejection fraction recovered to 50% on day 10. The biventricular assist device was successfully removed on day 14. She has not experienced worsening of biventricular function during her follow-ups for 4 years. CONCLUSIONS: Ventricular assist device therapy should be considered if there is no improvement in cardiac function in patients with fulminant myocarditis regardless of several days of support by venoarterial extracorporeal membrane oxygenation. A right ventricular assist device should always be implemented when necessary because biventricular involvement is not uncommon in fulminant myocarditis. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13256-017-1466-1) contains supplementary material, which is available to authorized users. BioMed Central 2017-10-24 /pmc/articles/PMC5654049/ /pubmed/29061186 http://dx.doi.org/10.1186/s13256-017-1466-1 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Adachi, Yusuke
Kinoshita, Osamu
Hatano, Masaru
Shintani, Yukako
Naito, Noritsugu
Kimura, Mitsutoshi
Nawata, Kan
Nitta, Daisuke
Maki, Hisataka
Ueda, Kazutaka
Amiya, Eisuke
Takimoto, Eiki
Komuro, Issei
Ono, Minoru
Successful bridge to recovery in fulminant myocarditis using a biventricular assist device: a case report
title Successful bridge to recovery in fulminant myocarditis using a biventricular assist device: a case report
title_full Successful bridge to recovery in fulminant myocarditis using a biventricular assist device: a case report
title_fullStr Successful bridge to recovery in fulminant myocarditis using a biventricular assist device: a case report
title_full_unstemmed Successful bridge to recovery in fulminant myocarditis using a biventricular assist device: a case report
title_short Successful bridge to recovery in fulminant myocarditis using a biventricular assist device: a case report
title_sort successful bridge to recovery in fulminant myocarditis using a biventricular assist device: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654049/
https://www.ncbi.nlm.nih.gov/pubmed/29061186
http://dx.doi.org/10.1186/s13256-017-1466-1
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