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Silencing HOXD10 by promoter region hypermethylation activates ERK signaling in hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma is the fifth most common malignancy and the third leading cause of cancer-related death worldwide. Dysregulation of HomeoboxD10 (HOXD10) was found to suppress or promote cancer progression in different cancer types. The function and regulation of HOXD10 remain un...

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Detalles Bibliográficos
Autores principales:	Guo, Yulin, Peng, Yaojun, Gao, Dan, Zhang, Meiying, Yang, Weili, Linghu, Enqiang, Herman, James G., Fuks, François, Dong, Guanglong, Guo, Mingzhou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654145/ https://www.ncbi.nlm.nih.gov/pubmed/29075359 http://dx.doi.org/10.1186/s13148-017-0412-9

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