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Hexvix blue light fluorescence cystoscopy – a promising approach in superficial bladder tumors diagnosis
Introduction: Nowadays, Hexvix blue light cystoscopy (BLC) represents an increasingly acknowledged diagnostic method for patients with bladder cancer. The aim of our study was to establish the place of this procedure in superficial bladder tumors diagnosis and to compare it with standard white light...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Carol Davila University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654302/ https://www.ncbi.nlm.nih.gov/pubmed/20108513 |
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author | B., Geavlete R., Mulţescu D., Georgescu P., Geavlete |
author_facet | B., Geavlete R., Mulţescu D., Georgescu P., Geavlete |
author_sort | B., Geavlete |
collection | PubMed |
description | Introduction: Nowadays, Hexvix blue light cystoscopy (BLC) represents an increasingly acknowledged diagnostic method for patients with bladder cancer. The aim of our study was to establish the place of this procedure in superficial bladder tumors diagnosis and to compare it with standard white light cystoscopy (WLC). Material and methods: Between December 2007 and January 2008, WLC and BLC were performed in 20 cases. Transurethral bladder resection (TURB) was performed for all apparent detected lesions. The patients diagnosed with superficial bladder tumors have been followed-up after 3 months by WLC and BLC. The control group included the same number of consecutive patients with superficial bladder tumors, diagnosed only by WLC, which underwent the same treatment and follow-up protocol as the study group. Results: WLC identified 30 suspicious lesions (28 pathologically confirmed), while BLC identified 41 apparent tumors (39 pathologically confirmed). So, from the total number of 40 tumors with positive histology, WLC correctly diagnosed 70% of them, with a rate of 6.7% false-positive results, while BLC diagnosed 97.5%, however presenting a 4.9% rate of false-positive results. 17 cases of the study group diagnosed with superficial bladder tumors were followed. The tumor recurrence rate after 3 months was 5.9% for the study group and 23.5% for the control group. Conclusions: Hexvix fluorescence cystoscopy is a valuable diagnostic method, with considerably better results by comparison to WLC. The improved diagnostic may have a significant impact upon the recurrence rate. |
format | Online Article Text |
id | pubmed-5654302 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | Carol Davila University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-56543022017-10-30 Hexvix blue light fluorescence cystoscopy – a promising approach in superficial bladder tumors diagnosis B., Geavlete R., Mulţescu D., Georgescu P., Geavlete J Med Life Special Articles Introduction: Nowadays, Hexvix blue light cystoscopy (BLC) represents an increasingly acknowledged diagnostic method for patients with bladder cancer. The aim of our study was to establish the place of this procedure in superficial bladder tumors diagnosis and to compare it with standard white light cystoscopy (WLC). Material and methods: Between December 2007 and January 2008, WLC and BLC were performed in 20 cases. Transurethral bladder resection (TURB) was performed for all apparent detected lesions. The patients diagnosed with superficial bladder tumors have been followed-up after 3 months by WLC and BLC. The control group included the same number of consecutive patients with superficial bladder tumors, diagnosed only by WLC, which underwent the same treatment and follow-up protocol as the study group. Results: WLC identified 30 suspicious lesions (28 pathologically confirmed), while BLC identified 41 apparent tumors (39 pathologically confirmed). So, from the total number of 40 tumors with positive histology, WLC correctly diagnosed 70% of them, with a rate of 6.7% false-positive results, while BLC diagnosed 97.5%, however presenting a 4.9% rate of false-positive results. 17 cases of the study group diagnosed with superficial bladder tumors were followed. The tumor recurrence rate after 3 months was 5.9% for the study group and 23.5% for the control group. Conclusions: Hexvix fluorescence cystoscopy is a valuable diagnostic method, with considerably better results by comparison to WLC. The improved diagnostic may have a significant impact upon the recurrence rate. Carol Davila University Press 2008-08-15 /pmc/articles/PMC5654302/ /pubmed/20108513 Text en ©Carol Davila University Press This article is distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/3.0/), which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Special Articles B., Geavlete R., Mulţescu D., Georgescu P., Geavlete Hexvix blue light fluorescence cystoscopy – a promising approach in superficial bladder tumors diagnosis |
title | Hexvix blue light fluorescence cystoscopy – a promising approach in superficial bladder tumors diagnosis
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title_full | Hexvix blue light fluorescence cystoscopy – a promising approach in superficial bladder tumors diagnosis
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title_fullStr | Hexvix blue light fluorescence cystoscopy – a promising approach in superficial bladder tumors diagnosis
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title_full_unstemmed | Hexvix blue light fluorescence cystoscopy – a promising approach in superficial bladder tumors diagnosis
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title_short | Hexvix blue light fluorescence cystoscopy – a promising approach in superficial bladder tumors diagnosis
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title_sort | hexvix blue light fluorescence cystoscopy – a promising approach in superficial bladder tumors diagnosis |
topic | Special Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654302/ https://www.ncbi.nlm.nih.gov/pubmed/20108513 |
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