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Transcriptional Coupling of Neighboring Genes and Gene Expression Noise: Evidence that Gene Orientation and Noncoding Transcripts Are Modulators of Noise

How is noise in gene expression modulated? Do mechanisms of noise control impact genome organization? In yeast, the expression of one gene can affect that of a very close neighbor. As the effect is highly regionalized, we hypothesize that genes in different orientations will have differing degrees o...

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Detalles Bibliográficos
Autores principales: Wang, Guang-Zhong, Lercher, Martin J., Hurst, Laurence D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654408/
https://www.ncbi.nlm.nih.gov/pubmed/21402863
http://dx.doi.org/10.1093/gbe/evr025

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