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Characterisation of the changing genomic landscape of metastatic melanoma using cell free DNA

Cancer is characterised by complex somatically acquired genetic aberrations that manifest as intra-tumour and inter-tumour genetic heterogeneity and can lead to treatment resistance. In this case study, we characterise the genome-wide somatic mutation dynamics in a metastatic melanoma patient during...

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Detalles Bibliográficos
Autores principales:	Cutts, Anthony, Venn, Oliver, Dilthey, Alexander, Gupta, Avinash, Vavoulis, Dimitris, Dreau, Helene, Middleton, Mark, McVean, Gil, Taylor, Jenny C., Schuh, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654504/ https://www.ncbi.nlm.nih.gov/pubmed/29075515 http://dx.doi.org/10.1038/s41525-017-0030-7

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