Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist

Urinary tract infections (UTI) caused by uropathogenic E. coli (UPEC) affect 150 million people annually(1,2). Despite effective antibiotic therapy, 30–50% of patients experience recurrent UTI (rUTI)(1). Additionally, the growing prevelance of UPEC resistant to last-line antibiotic treatments, and m...

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Detalles Bibliográficos
Autores principales: Spaulding, Caitlin N., Klein, Roger D., Ruer, Ségolène, Kau, Andrew L., Schreiber, Henry L., Cusumano, Zachary T., Dodson, Karen W., Pinkner, Jerome S., Fremont, Daved H., Janetka, James W., Remaut, Han, Gordon, Jeffrey I., Hultgren, Scott J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654549/
https://www.ncbi.nlm.nih.gov/pubmed/28614296
http://dx.doi.org/10.1038/nature22972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654549/
https://www.ncbi.nlm.nih.gov/pubmed/28614296
http://dx.doi.org/10.1038/nature22972

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