Cargando…

Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist

Urinary tract infections (UTI) caused by uropathogenic E. coli (UPEC) affect 150 million people annually(1,2). Despite effective antibiotic therapy, 30–50% of patients experience recurrent UTI (rUTI)(1). Additionally, the growing prevelance of UPEC resistant to last-line antibiotic treatments, and m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Spaulding, Caitlin N., Klein, Roger D., Ruer, Ségolène, Kau, Andrew L., Schreiber, Henry L., Cusumano, Zachary T., Dodson, Karen W., Pinkner, Jerome S., Fremont, Daved H., Janetka, James W., Remaut, Han, Gordon, Jeffrey I., Hultgren, Scott J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654549/ https://www.ncbi.nlm.nih.gov/pubmed/28614296 http://dx.doi.org/10.1038/nature22972

Ejemplares similares

Evolutionary fine-tuning of conformational ensembles in FimH during host-pathogen interactions
por: Kalas, Vasilios, et al.
Publicado: (2017)

Insightful Improvement in the Design of Potent Uropathogenic E. coli FimH Antagonists
por: Mousavifar, Leila, et al.
Publicado: (2023)

Cloning of fimH and fliC and expression of the fusion protein FimH/FliC from Uropathogenic Escherichia coli (UPEC) isolated in Iran
por: Asadi, Karam MR, et al.
Publicado: (2012)

FimH and Anti-Adhesive Therapeutics: A Disarming Strategy Against Uropathogens
por: Sarshar, Meysam, et al.
Publicado: (2020)

D-Mannoside FimH Inhibitors as Non-Antibiotic Alternatives for Uropathogenic Escherichia coli
por: Montes-Robledo, Alfredo, et al.
Publicado: (2021)

The FimH Gene in Uropathogenic Escherichia coli Strains Isolated From Patients With Urinary Tract Infection
por: Hojati, Zohreh, et al.
Publicado: (2015)

FimH and Type 1 Pili Mediated Tumor Cell Cytotoxicity by Uropathogenic Escherichia coli In Vitro
por: Van Eyssen, Shelly Roselyn, et al.
Publicado: (2023)

Inhibition and Reversal of Microbial Attachment by an Antibody with Parasteric Activity against the FimH Adhesin of Uropathogenic E. coli
por: Kisiela, Dagmara I., et al.
Publicado: (2015)

Bacterial Lectin FimH and Its Aggregation Hot-Spots: An Alternative Strategy against Uropathogenic Escherichia coli
por: Nasi, Georgia I., et al.
Publicado: (2023)

Catch-bond mechanism of the bacterial adhesin FimH
por: Sauer, Maximilian M., et al.
Publicado: (2016)

FimH as a scaffold for regulated molecular recognition
por: Ludwig, Shivani Gupta, et al.
Publicado: (2021)

CRISPRi Induced Suppression of Fimbriae Gene (fimH) of a Uropathogenic Escherichia coli: An Approach to Inhibit Microbial Biofilms
por: Zuberi, Azna, et al.
Publicado: (2017)

d-Mannose Treatment neither Affects Uropathogenic Escherichia coli Properties nor Induces Stable FimH Modifications
por: Scribano, Daniela, et al.
Publicado: (2020)

Comparative Study of Aryl O-, C-, and S-Mannopyranosides as Potential Adhesion Inhibitors toward Uropathogenic E. coli FimH
por: Mousavifar, Leila, et al.
Publicado: (2019)

Crystal structure of the FimD usher bound to its cognate FimC:FimH substrate
por: Phan, Gilles, et al.
Publicado: (2011)

En route to photoaffinity labeling of the bacterial lectin FimH
por: Lindhorst, Thisbe K, et al.
Publicado: (2010)

Diazirine-functionalized mannosides for photoaffinity labeling: trouble with FimH
por: Beiroth, Femke, et al.
Publicado: (2018)

FimH-based display of functional eukaryotic proteins on bacteria surfaces
por: Chmielewski, Markus, et al.
Publicado: (2019)

Escherichia coli adhesion portion FimH functions as an adjuvant for cancer immunotherapy
por: Zhang, Wei, et al.
Publicado: (2020)

Transcriptional Response Of E. coli Upon FimH-mediated Fimbrial Adhesion
por: Bhomkar, Prasanna, et al.
Publicado: (2010)

Are D-manno-configured Amadori products ligands of the bacterial lectin FimH?
por: Gloe, Tobias-Elias, et al.
Publicado: (2015)

A Novel Integrated Way for Deciphering the Glycan Code for the FimH Lectin
por: Dumych, Tetiana, et al.
Publicado: (2018)

Blockage of bacterial FimH prevents mucosal inflammation associated with Crohn’s disease
por: Chevalier, Grégoire, et al.
Publicado: (2021)

Intervening with Urinary Tract Infections Using Anti-Adhesives Based on the Crystal Structure of the FimH–Oligomannose-3 Complex
por: Wellens, Adinda, et al.
Publicado: (2008)

In silico design of fusion protein of FimH from uropathogenic Escherichia coli and MrpH from Proteus mirabilis against urinary tract infections
por: Habibi, Mehri, et al.
Publicado: (2015)

Correction: Intervening with Urinary Tract Infections Using Anti-Adhesives Based on the Crystal Structure of the FimH–Oligomannose-3 Complex
por: Wellens, Adinda, et al.
Publicado: (2008)

Biocomputational Prediction Approach Targeting FimH by Natural SGLT2 Inhibitors: A Possible Way to Overcome the Uropathogenic Effect of SGLT2 Inhibitor Drugs
por: Mashraqi, Mutaib M., et al.
Publicado: (2021)

A bivalent glycopeptide to target two putative carbohydrate binding sites on FimH
por: Lindhorst, Thisbe K, et al.
Publicado: (2010)

Synthesis and testing of the first azobenzene mannobioside as photoswitchable ligand for the bacterial lectin FimH
por: Chandrasekaran, Vijayanand, et al.
Publicado: (2013)

The affinity of the FimH fimbrial adhesin is receptor-driven and quasi-independent of Escherichia coli pathotypes
por: Bouckaert, Julie, et al.
Publicado: (2006)

Structures of C-mannosylated anti-adhesives bound to the type 1 fimbrial FimH adhesin
por: de Ruyck, Jerome, et al.
Publicado: (2016)

Molecular docking and simulation analysis of the FimH protein with secondary metabolites from the Garcinia species
por: Badiger, Abhijeeth S, et al.
Publicado: (2022)

Precision antimicrobial therapeutics: the path of least resistance?
por: Spaulding, Caitlin N., et al.
Publicado: (2018)

Adhesion of Escherichia coli under flow conditions reveals potential novel effects of FimH mutations
por: Feenstra, T., et al.
Publicado: (2016)

Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH
por: Stsiapanava, Alena, et al.
Publicado: (2022)

FimH confers mannose-targeting ability to Bacillus Calmette-Guerin for improved immunotherapy in bladder cancer
por: Zhang, Yang, et al.
Publicado: (2022)

Selection for nonspecific adhesion is a driver of FimH evolution increasing Escherichia coli biofilm capacity
por: Yoshida, Mari, et al.
Publicado: (2022)

Pilicide ec240 Disrupts Virulence Circuits in Uropathogenic Escherichia coli
por: Greene, Sarah E., et al.
Publicado: (2014)

Insights from the molecular docking analysis of SGLT2 and FIMH to combat uropathogenicity
por: Abdulaal, Wesam H, et al.
Publicado: (2022)

Context-Dependent Requirements for FimH and Other Canonical Virulence Factors in Gut Colonization by Extraintestinal Pathogenic Escherichia coli
por: Russell, Colin W., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ev9pc5uso6j320phqa3n5rukmi