Mitotic Disassembly of Nuclear Pore Complexes Involves CDK1- and PLK1-Mediated Phosphorylation of Key Interconnecting Nucleoporins

During interphase, the nuclear envelope (NE) serves as a selective barrier between cytosol and nucleoplasm. When vertebrate cells enter mitosis, the NE is dismantled in the process of nuclear envelope breakdown (NEBD). Disassembly of nuclear pore complexes (NPCs) is a key aspect of NEBD, required fo...

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Detalles Bibliográficos
Autores principales: Linder, Monika I., Köhler, Mario, Boersema, Paul, Weberruss, Marion, Wandke, Cornelia, Marino, Joseph, Ashiono, Caroline, Picotti, Paola, Antonin, Wolfram, Kutay, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654724/
https://www.ncbi.nlm.nih.gov/pubmed/29065306
http://dx.doi.org/10.1016/j.devcel.2017.08.020

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