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Mitochondrial Ferredoxin Determines Vulnerability of Cells to Copper Excess
The essential micronutrient copper is tightly regulated in organisms, as environmental exposure or homeostasis defects can cause toxicity and neurodegenerative disease. The principal target(s) of copper toxicity have not been pinpointed, but one key effect is impaired supply of iron-sulfur (FeS) clu...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cell Press
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654725/ https://www.ncbi.nlm.nih.gov/pubmed/28867595 http://dx.doi.org/10.1016/j.chembiol.2017.08.005 |