‘Hotspots’ of Antigen Presentation Revealed by Human Leukocyte Antigen Ligandomics for Neoantigen Prioritization

The remarkable clinical efficacy of the immune checkpoint blockade therapies has motivated researchers to discover immunogenic epitopes and exploit them for personalized vaccines. Human leukocyte antigen (HLA)-binding peptides derived from processing and presentation of mutated proteins are one of t...

Descripción completa

Detalles Bibliográficos
Autores principales: Müller, Markus, Gfeller, David, Coukos, George, Bassani-Sternberg, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654951/
https://www.ncbi.nlm.nih.gov/pubmed/29104575
http://dx.doi.org/10.3389/fimmu.2017.01367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654951/
https://www.ncbi.nlm.nih.gov/pubmed/29104575
http://dx.doi.org/10.3389/fimmu.2017.01367

Ejemplares similares