Phosphoinositide-specific phospholipase Cγ1 inhibition induces autophagy in human colon cancer and hepatocellular carcinoma cells

Phosphoinositide-specific phospholipase C (PLC) γ1 has been reported to be involved in cancer cell proliferation and metastasis. However, whether PLCγ1 modulates autophagy and the underlying mechanism remains unclear. Here, we investigated the relationship between PLCγ1 and autophagy in the human co...

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Detalles Bibliográficos
Autores principales: Dai, Lianzhi, Chen, Xiaolei, Lu, Xiaohong, Wang, Fen, Zhan, Yanyan, Song, Gang, Hu, Tianhui, Xia, Chun, Zhang, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654964/
https://www.ncbi.nlm.nih.gov/pubmed/29066806
http://dx.doi.org/10.1038/s41598-017-13334-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654964/
https://www.ncbi.nlm.nih.gov/pubmed/29066806
http://dx.doi.org/10.1038/s41598-017-13334-y

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