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Phosphoinositide-specific phospholipase Cγ1 inhibition induces autophagy in human colon cancer and hepatocellular carcinoma cells
Phosphoinositide-specific phospholipase C (PLC) γ1 has been reported to be involved in cancer cell proliferation and metastasis. However, whether PLCγ1 modulates autophagy and the underlying mechanism remains unclear. Here, we investigated the relationship between PLCγ1 and autophagy in the human co...
Autores principales: | Dai, Lianzhi, Chen, Xiaolei, Lu, Xiaohong, Wang, Fen, Zhan, Yanyan, Song, Gang, Hu, Tianhui, Xia, Chun, Zhang, Bing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654964/ https://www.ncbi.nlm.nih.gov/pubmed/29066806 http://dx.doi.org/10.1038/s41598-017-13334-y |
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