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Calcineurin/P-ERK/Egr-1 Pathway is Involved in Fear Memory Impairment after Isoflurane Exposure in Mice

Isoflurane exposure adversely influences subsequent fear memory formation in mice. Calcineurin (CaN), a phosphatase, prevents the establishment of emotional memory by dephosphorylating substrates and inhibiting the expression of learning and memory related genes. We investigated whether isoflurane i...

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Detalles Bibliográficos
Autores principales:	Yang, Xiaoxuan, Li, Guohui, Xue, Qingsheng, Luo, Yan, Wang, Sensen, Xia, Yimeng, Zhuang, Lei, Yu, Buwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654981/ https://www.ncbi.nlm.nih.gov/pubmed/29066839 http://dx.doi.org/10.1038/s41598-017-13975-z

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