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Simultaneous Quantification of Spatially Discordant Alternans in Voltage and Intracellular Calcium in Langendorff-Perfused Rabbit Hearts and Inconsistencies with Models of Cardiac Action Potentials and Ca Transients
Rationale: Discordant alternans, a phenomenon in which the action potential duration (APDs) and/or intracellular calcium transient durations (CaDs) in different spatial regions of cardiac tissue are out of phase, present a dynamical instability for complex spatial dispersion that can be associated w...
Autores principales: | Uzelac, Ilija, Ji, Yanyan C., Hornung, Daniel, Schröder-Scheteling, Johannes, Luther, Stefan, Gray, Richard A., Cherry, Elizabeth M., Fenton, Flavio H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655020/ https://www.ncbi.nlm.nih.gov/pubmed/29104543 http://dx.doi.org/10.3389/fphys.2017.00819 |
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