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Cell Type-Specific mRNA Dysregulation in Hippocampal CA1 Pyramidal Neurons of the Fragile X Syndrome Mouse Model

Fragile X syndrome (FXS) is a genetic disorder due to the silencing of the Fmr1 gene, causing intellectual disability, seizures, hyperactivity, and social anxiety. All these symptoms result from the loss of expression of the RNA binding protein fragile X mental retardation protein (FMRP), which alte...

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Detalles Bibliográficos
Autores principales:	Ceolin, Laura, Bouquier, Nathalie, Vitre-Boubaker, Jihane, Rialle, Stéphanie, Severac, Dany, Valjent, Emmanuel, Perroy, Julie, Puighermanal, Emma
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655025/ https://www.ncbi.nlm.nih.gov/pubmed/29104533 http://dx.doi.org/10.3389/fnmol.2017.00340

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