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Vorinostat-eluting poly(DL-lactide-co-glycolide) nanofiber-coated stent for inhibition of cholangiocarcinoma cells

PURPOSE: The aim of this study was to fabricate a vorinostat (Zolinza™)-eluting nanofiber membrane-coated gastrointestinal (GI) stent and to study its antitumor activity against cholangiocarcinoma (CCA) cells in vitro and in vivo. METHODS: Vorinostat and poly(DL-lactide-co-glycolide) dissolved in an...

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Detalles Bibliográficos
Autores principales: Kwak, Tae Won, Lee, Hye Lim, Song, Yeon Hui, Kim, Chan, Kim, Jungsoo, Seo, Sol-Ji, Jeong, Young-Il, Kang, Dae Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655133/
https://www.ncbi.nlm.nih.gov/pubmed/29089762
http://dx.doi.org/10.2147/IJN.S141920