The role of EGFR double minutes in modulating the response of malignant gliomas to radiotherapy

EGFR amplification in cells having double minute chromosomes (DM) is commonly found in glioblastoma multiforme (GBM); however, how much it contributes to the current failure to treat GBM successfully is unknown. We studied two syngeneic primary cultures derived from a GBM with and without cells carr...

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Detalles Bibliográficos
Autores principales: Zhou, Yi-Hong, Chen, Yumay, Hu, Yuanjie, Yu, Liping, Tran, Katherine, Giedzinski, Erich, Ru, Ning, Gau, Alex, Pan, Francine, Qiao, Jiao, Atkin, Naomi, Ly, Khang Chi, Lee, Nathan, Siegel, Eric R., Linskey, Mark E., Wang, Ping, Limoli, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655244/
https://www.ncbi.nlm.nih.gov/pubmed/29113349
http://dx.doi.org/10.18632/oncotarget.20714

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