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6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase isoform 3 spatially mediates autophagy through the AMPK signaling pathway

6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase isoform 3 (PFKFB3), is a critical enzyme for glycolysis and highly expressed in cancer cells. It plays an essential role in regulating metabolism, angiogenesis, and inflammation. Although PFKFB3 is involved in modulating autophagy, its regulatory...

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Detalles Bibliográficos
Autores principales: Yan, Siyuan, Wei, Xiaoli, Xu, Shanshan, Sun, Hui, Wang, Weijun, Liu, Ling, Jiang, Xuejun, Zhang, Yongxiang, Che, Yongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655249/
https://www.ncbi.nlm.nih.gov/pubmed/29113354
http://dx.doi.org/10.18632/oncotarget.20757