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Internal mammary lymph nodes radiotherapy of breast cancer in the era of individualized medicine
Inclusion internal mammary lymph nodes as a part of regional nodal irradiation have a potential to reduce local recurrence, distant recurrence, and improve survival in breast cancer. However, the increased risk of cardiac toxicity and lungs injure associated with internal mammary lymph nodes irradia...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655311/ https://www.ncbi.nlm.nih.gov/pubmed/29113416 http://dx.doi.org/10.18632/oncotarget.20186 |
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author | Cong, Bin-Bin Cao, Xiao-Shan Cao, Lu Zhu, Hui Yu, Yi-Shan Yu, Jin-Ming Wang, Yong-Sheng |
author_facet | Cong, Bin-Bin Cao, Xiao-Shan Cao, Lu Zhu, Hui Yu, Yi-Shan Yu, Jin-Ming Wang, Yong-Sheng |
author_sort | Cong, Bin-Bin |
collection | PubMed |
description | Inclusion internal mammary lymph nodes as a part of regional nodal irradiation have a potential to reduce local recurrence, distant recurrence, and improve survival in breast cancer. However, the increased risk of cardiac toxicity and lungs injure associated with internal mammary lymph nodes irradiation has drew more and more attention. Estimating risk of metastasis in internal mammary lymph nodes based on axillary lymph nodes metastasis status is not always reliable: low-risk do not always mean negative in internal mammary lymph nodes and high-risk do not always indicate positive in internal mammary lymph nodes. Inaccurate prediction of in internal mammary lymph nodes metastasis might lead to over- or under-treatment of in internal mammary lymph node. Internal mammary sentinel lymph node biopsy is a minimally invasive technique which has a high potential to accurately evaluate the metastasis status in in internal mammary lymph nodes and improve accuracy of nodal staging. This technique might be a useful tool to guide individualized internal mammary lymph nodes irradiation. |
format | Online Article Text |
id | pubmed-5655311 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Impact Journals LLC |
record_format | MEDLINE/PubMed |
spelling | pubmed-56553112017-11-06 Internal mammary lymph nodes radiotherapy of breast cancer in the era of individualized medicine Cong, Bin-Bin Cao, Xiao-Shan Cao, Lu Zhu, Hui Yu, Yi-Shan Yu, Jin-Ming Wang, Yong-Sheng Oncotarget Review Inclusion internal mammary lymph nodes as a part of regional nodal irradiation have a potential to reduce local recurrence, distant recurrence, and improve survival in breast cancer. However, the increased risk of cardiac toxicity and lungs injure associated with internal mammary lymph nodes irradiation has drew more and more attention. Estimating risk of metastasis in internal mammary lymph nodes based on axillary lymph nodes metastasis status is not always reliable: low-risk do not always mean negative in internal mammary lymph nodes and high-risk do not always indicate positive in internal mammary lymph nodes. Inaccurate prediction of in internal mammary lymph nodes metastasis might lead to over- or under-treatment of in internal mammary lymph node. Internal mammary sentinel lymph node biopsy is a minimally invasive technique which has a high potential to accurately evaluate the metastasis status in in internal mammary lymph nodes and improve accuracy of nodal staging. This technique might be a useful tool to guide individualized internal mammary lymph nodes irradiation. Impact Journals LLC 2017-08-11 /pmc/articles/PMC5655311/ /pubmed/29113416 http://dx.doi.org/10.18632/oncotarget.20186 Text en Copyright: © 2017 Cong et al. http://creativecommons.org/licenses/by/3.0/ This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/) (CC-BY), which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Review Cong, Bin-Bin Cao, Xiao-Shan Cao, Lu Zhu, Hui Yu, Yi-Shan Yu, Jin-Ming Wang, Yong-Sheng Internal mammary lymph nodes radiotherapy of breast cancer in the era of individualized medicine |
title | Internal mammary lymph nodes radiotherapy of breast cancer in the era of individualized medicine |
title_full | Internal mammary lymph nodes radiotherapy of breast cancer in the era of individualized medicine |
title_fullStr | Internal mammary lymph nodes radiotherapy of breast cancer in the era of individualized medicine |
title_full_unstemmed | Internal mammary lymph nodes radiotherapy of breast cancer in the era of individualized medicine |
title_short | Internal mammary lymph nodes radiotherapy of breast cancer in the era of individualized medicine |
title_sort | internal mammary lymph nodes radiotherapy of breast cancer in the era of individualized medicine |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655311/ https://www.ncbi.nlm.nih.gov/pubmed/29113416 http://dx.doi.org/10.18632/oncotarget.20186 |
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