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Anti-tumor Study of Chondroitin Sulfate-Methotrexate Nanogels

Self-assembly nanogels (NGs) were formed by bioconjugating methotrexate (MTX) with chondroitin sulfate (CS). MTX-CS NGs can greatly enhance the solubility and improve the delivery efficacy of MTX due to the CD44 binding property of CS. Vivo experiments revealed that MTX-CS NGs showed less toxicity t...

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Detalles Bibliográficos
Autores principales:	Wang, Jinyu, Zhao, Weibo, Chen, Haixiao, Qin, An, Zhu, Peizhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2017
Materias:	Nano Express
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655378/ https://www.ncbi.nlm.nih.gov/pubmed/29067569 http://dx.doi.org/10.1186/s11671-017-2324-1

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