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PRMT5: A novel regulator of Hepatitis B virus replication and an arginine methylase of HBV core

In mammals, protein arginine methyltransferase 5, PRMT5, is the main type II enzyme responsible for the majority of symmetric dimethylarginine formation in polypeptides. Recent study reported that PRMT5 restricts Hepatitis B virus (HBV) replication through epigenetic repression of HBV DNA transcript...

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Detalles Bibliográficos
Autores principales: Lubyova, Barbora, Hodek, Jan, Zabransky, Ales, Prouzova, Hana, Hubalek, Martin, Hirsch, Ivan, Weber, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655436/
https://www.ncbi.nlm.nih.gov/pubmed/29065155
http://dx.doi.org/10.1371/journal.pone.0186982