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A Proposal of an Effective Platelet-rich Plasma Protocol for the Treatment of Androgenetic Alopecia
BACKGROUND: Platelet-rich plasma (PRP) has emerged as a promising treatment for androgenetic alopecia (AGA). In spite of the several studies previously reported, to date, a standardized protocol for PRP preparation and application, as well as a standard method for evaluating results has not been est...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655625/ https://www.ncbi.nlm.nih.gov/pubmed/29118521 http://dx.doi.org/10.4103/ijt.ijt_27_17 |
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author | Ferrando, Juan García-García, Sandra Cecilia González-de-Cossío, Ana Cecilia Bou, Lola Navarra, Esperanza |
author_facet | Ferrando, Juan García-García, Sandra Cecilia González-de-Cossío, Ana Cecilia Bou, Lola Navarra, Esperanza |
author_sort | Ferrando, Juan |
collection | PubMed |
description | BACKGROUND: Platelet-rich plasma (PRP) has emerged as a promising treatment for androgenetic alopecia (AGA). In spite of the several studies previously reported, to date, a standardized protocol for PRP preparation and application, as well as a standard method for evaluating results has not been established. AIMS: The aim of this study is to propose a standardized method for preparation and application of PRP for male AGA (MAGA) and female AGA (FAGA) and assess its safety and efficacy as a co-adjuvant therapy. MATERIALS AND METHODS: Seventy-eight patients, 19 men and 59 women with AGA Grades II–IV in Ebling's scale, currently on treatment with topical minoxidil and/or oral finasteride for more than a year without improvement, were included in this study. PRP was prepared using a single spin method, and injected in affected areas for 3 monthly sessions, followed by 3 bimonthly sessions. A decrease of at least one grade in Ebling's scale was considered a successful result. RESULTS: After the 6° session, 71.4% of MAGA and 73.4% of FAGA patients reached a successful outcome while 21.4% and 16.3%, respectively, remained without changes. Only 7.1% of MAGA and 10.2% of FAGA presented worsening of their condition. CONCLUSIONS: PRP together with a periodical application protocol can be considered effective as a coadjuvant therapy in patients who no longer respond to pharmacological treatments. Ebling's scale was a practical and reliable parameter to allow a better evaluation in both MAGA and FAGA. |
format | Online Article Text |
id | pubmed-5655625 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-56556252017-11-08 A Proposal of an Effective Platelet-rich Plasma Protocol for the Treatment of Androgenetic Alopecia Ferrando, Juan García-García, Sandra Cecilia González-de-Cossío, Ana Cecilia Bou, Lola Navarra, Esperanza Int J Trichology Original Article BACKGROUND: Platelet-rich plasma (PRP) has emerged as a promising treatment for androgenetic alopecia (AGA). In spite of the several studies previously reported, to date, a standardized protocol for PRP preparation and application, as well as a standard method for evaluating results has not been established. AIMS: The aim of this study is to propose a standardized method for preparation and application of PRP for male AGA (MAGA) and female AGA (FAGA) and assess its safety and efficacy as a co-adjuvant therapy. MATERIALS AND METHODS: Seventy-eight patients, 19 men and 59 women with AGA Grades II–IV in Ebling's scale, currently on treatment with topical minoxidil and/or oral finasteride for more than a year without improvement, were included in this study. PRP was prepared using a single spin method, and injected in affected areas for 3 monthly sessions, followed by 3 bimonthly sessions. A decrease of at least one grade in Ebling's scale was considered a successful result. RESULTS: After the 6° session, 71.4% of MAGA and 73.4% of FAGA patients reached a successful outcome while 21.4% and 16.3%, respectively, remained without changes. Only 7.1% of MAGA and 10.2% of FAGA presented worsening of their condition. CONCLUSIONS: PRP together with a periodical application protocol can be considered effective as a coadjuvant therapy in patients who no longer respond to pharmacological treatments. Ebling's scale was a practical and reliable parameter to allow a better evaluation in both MAGA and FAGA. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5655625/ /pubmed/29118521 http://dx.doi.org/10.4103/ijt.ijt_27_17 Text en Copyright: © 2017 International Journal of Trichology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Ferrando, Juan García-García, Sandra Cecilia González-de-Cossío, Ana Cecilia Bou, Lola Navarra, Esperanza A Proposal of an Effective Platelet-rich Plasma Protocol for the Treatment of Androgenetic Alopecia |
title | A Proposal of an Effective Platelet-rich Plasma Protocol for the Treatment of Androgenetic Alopecia |
title_full | A Proposal of an Effective Platelet-rich Plasma Protocol for the Treatment of Androgenetic Alopecia |
title_fullStr | A Proposal of an Effective Platelet-rich Plasma Protocol for the Treatment of Androgenetic Alopecia |
title_full_unstemmed | A Proposal of an Effective Platelet-rich Plasma Protocol for the Treatment of Androgenetic Alopecia |
title_short | A Proposal of an Effective Platelet-rich Plasma Protocol for the Treatment of Androgenetic Alopecia |
title_sort | proposal of an effective platelet-rich plasma protocol for the treatment of androgenetic alopecia |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655625/ https://www.ncbi.nlm.nih.gov/pubmed/29118521 http://dx.doi.org/10.4103/ijt.ijt_27_17 |
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