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GRcalculator: an online tool for calculating and mining dose–response data

BACKGROUND: Quantifying the response of cell lines to drugs or other perturbagens is the cornerstone of pre-clinical drug development and pharmacogenomics as well as a means to study factors that contribute to sensitivity and resistance. In dividing cells, traditional metrics derived from dose–respo...

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Detalles Bibliográficos
Autores principales: Clark, Nicholas A., Hafner, Marc, Kouril, Michal, Williams, Elizabeth H., Muhlich, Jeremy L., Pilarczyk, Marcin, Niepel, Mario, Sorger, Peter K., Medvedovic, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655815/
https://www.ncbi.nlm.nih.gov/pubmed/29065900
http://dx.doi.org/10.1186/s12885-017-3689-3