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GRcalculator: an online tool for calculating and mining dose–response data
BACKGROUND: Quantifying the response of cell lines to drugs or other perturbagens is the cornerstone of pre-clinical drug development and pharmacogenomics as well as a means to study factors that contribute to sensitivity and resistance. In dividing cells, traditional metrics derived from dose–respo...
Autores principales: | Clark, Nicholas A., Hafner, Marc, Kouril, Michal, Williams, Elizabeth H., Muhlich, Jeremy L., Pilarczyk, Marcin, Niepel, Mario, Sorger, Peter K., Medvedovic, Mario |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655815/ https://www.ncbi.nlm.nih.gov/pubmed/29065900 http://dx.doi.org/10.1186/s12885-017-3689-3 |
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