Exploratory Population PK Analysis of Dupilumab, a Fully Human Monoclonal Antibody Against IL‐4Rα, in Atopic Dermatitis Patients and Normal Volunteers

An exploratory population pharmacokinetic model for functional dupilumab was developed. Data from healthy volunteers and patients with atopic dermatitis (AD) receiving intravenous or subcutaneous doses were integrated. The data included 197 participants (2,518 measurements of dupilumab in serum) fro...

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Detalles Bibliográficos
Autores principales: Kovalenko, P, DiCioccio, AT, Davis, JD, Li, M, Ardeleanu, M, Graham, NMH, Soltys, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655850/
https://www.ncbi.nlm.nih.gov/pubmed/27778477
http://dx.doi.org/10.1002/psp4.12136

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