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Current understanding of the molecular mechanisms in Parkinson's disease: Targets for potential treatments
Gradual degeneration and loss of dopaminergic neurons in the substantia nigra, pars compacta and subsequent reduction of dopamine levels in striatum are associated with motor deficits that characterize Parkinson’s disease (PD). In addition, half of the PD patients also exhibit frontostriatal-mediate...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655877/ https://www.ncbi.nlm.nih.gov/pubmed/29090092 http://dx.doi.org/10.1186/s40035-017-0099-z |