Cargando…

Current understanding of the molecular mechanisms in Parkinson's disease: Targets for potential treatments

Gradual degeneration and loss of dopaminergic neurons in the substantia nigra, pars compacta and subsequent reduction of dopamine levels in striatum are associated with motor deficits that characterize Parkinson’s disease (PD). In addition, half of the PD patients also exhibit frontostriatal-mediate...

Descripción completa

Detalles Bibliográficos
Autores principales: Maiti, Panchanan, Manna, Jayeeta, Dunbar, Gary L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655877/
https://www.ncbi.nlm.nih.gov/pubmed/29090092
http://dx.doi.org/10.1186/s40035-017-0099-z