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Gastrointestinal toxicity among patients taking selective COX‐2 inhibitors or conventional NSAIDs, alone or combined with proton pump inhibitors: a case–control study

PURPOSE: To assess the risk of gastrointestinal perforation, ulcers, or bleeding (PUB) associated with the use of conventional nonsteroidal anti‐inflammatory drugs (NSAIDs) with proton pump inhibitors (PPIs) and selective COX‐2 inhibitors, with or without PPIs compared with conventional NSAIDs. METH...

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Detalles Bibliográficos
Autores principales: Bakhriansyah, Mohammad, Souverein, Patrick C., de Boer, Anthonius, Klungel, Olaf H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655916/
https://www.ncbi.nlm.nih.gov/pubmed/28370857
http://dx.doi.org/10.1002/pds.4183