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The Repression of Atoh1 by Neurogenin1 during Inner Ear Development

Atonal homolog 1 (Atoh1) and Neurogenin1 (Neurog1) are basic Helix-Loop-Helix (bHLH) transcription factors crucial for the generation of hair cells (HCs) and neurons in the inner ear. Both genes are induced early in development, but the expression of Atoh1 is counteracted by Neurog1. As a result, HC...

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Detalles Bibliográficos
Autores principales:	Gálvez, Héctor, Tena, Juan J., Giraldez, Fernando, Abelló, Gina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655970/ https://www.ncbi.nlm.nih.gov/pubmed/29104531 http://dx.doi.org/10.3389/fnmol.2017.00321

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