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Chronic hepatitis B carriers with acute on chronic liver failure show increased HBV surface gene mutations, including immune escape variants

BACKGROUND: The pathogenesis of acute-on-chronic liver failure (ACLF) in chronic hepatitis B (CHB) is not well understood. The aim of this study was to investigate whether there is an association between HBV polymerase (P)/overlapping surface (S) gene and basal core promoter (BCP)/precore (PC) varia...

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Detalles Bibliográficos
Autores principales:	Gao, Shan, Joshi, Shivali S., Osiowy, Carla, Chen, Y., Coffin, Carla S., Duan, Z-P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655973/ https://www.ncbi.nlm.nih.gov/pubmed/29065883 http://dx.doi.org/10.1186/s12985-017-0870-x

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