A heuristic model for computational prediction of human branch point sequence

BACKGROUND: Pre-mRNA splicing is the removal of introns from precursor mRNAs (pre-mRNAs) and the concurrent ligation of the flanking exons to generate mature mRNA. This process is catalyzed by the spliceosome, where the splicing factor 1 (SF1) specifically recognizes the seven-nucleotide branch poin...

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Detalles Bibliográficos
Autores principales: Wen, Jia, Wang, Jue, Zhang, Qing, Guo, Dianjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655975/
https://www.ncbi.nlm.nih.gov/pubmed/29065858
http://dx.doi.org/10.1186/s12859-017-1864-9

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