A Water-Bridged Cysteine-Cysteine Redox Regulation Mechanism in Bacterial Protein Tyrosine Phosphatases

The emergence of multidrug-resistant Mycobacterium tuberculosis (Mtb) strains highlights the need to develop more efficacious and potent drugs. However, this goal is dependent on a comprehensive understanding of Mtb virulence protein effectors at the molecular level. Here, we used a post-expression...

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Detalles Bibliográficos
Autores principales: Bertoldo, Jean B., Rodrigues, Tiago, Dunsmore, Lavinia, Aprile, Francesco A., Marques, Marta C., Rosado, Leonardo A., Boutureira, Omar, Steinbrecher, Thomas B., Sherman, Woody, Corzana, Francisco, Terenzi, Hernán, Bernardes, Gonçalo J.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656095/
https://www.ncbi.nlm.nih.gov/pubmed/29094109
http://dx.doi.org/10.1016/j.chempr.2017.07.009

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