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Chloromethyl-triazole: a new motif for site-selective pseudo-acylation of proteins
Rapid, site-selective modification of cysteine residues with chloromethyl-triazole derivatives generates pseudo-acyl sLys motifs, mimicking important post-translational modifications. Near-native biotinylation of peptide and protein substrates is shown to be site-selective and modified histone H4 re...
Autores principales: | Brewster, Richard C., Gavins, Georgina C., Günthardt, Barbara, Farr, Sarah, Webb, Kimberly M., Voigt, Philipp, Hulme, Alison N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656099/ https://www.ncbi.nlm.nih.gov/pubmed/27722332 http://dx.doi.org/10.1039/c6cc06801d |
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