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Characteristics and outcomes of cholangiocarcinoma by region in Thailand: A nationwide study

AIM: To identify the potential risk factors of cholangiocarcinoma, we determined the characteristics of cholangiocarcinoma patients among 5 different regions of Thailand. METHODS: All patients diagnosed with cholangiocarcinoma between 2008 and 2013 were identified using the Nationwide Hospital Admis...

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Autores principales: Chaiteerakij, Roongruedee, Pan-ngum, Wirichada, Poovorawan, Kittiyod, Soonthornworasiri, Ngamphol, Treeprasertsuk, Sombat, Phaosawasdi, Kamthorn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656463/
https://www.ncbi.nlm.nih.gov/pubmed/29093624
http://dx.doi.org/10.3748/wjg.v23.i39.7160
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author Chaiteerakij, Roongruedee
Pan-ngum, Wirichada
Poovorawan, Kittiyod
Soonthornworasiri, Ngamphol
Treeprasertsuk, Sombat
Phaosawasdi, Kamthorn
author_facet Chaiteerakij, Roongruedee
Pan-ngum, Wirichada
Poovorawan, Kittiyod
Soonthornworasiri, Ngamphol
Treeprasertsuk, Sombat
Phaosawasdi, Kamthorn
author_sort Chaiteerakij, Roongruedee
collection PubMed
description AIM: To identify the potential risk factors of cholangiocarcinoma, we determined the characteristics of cholangiocarcinoma patients among 5 different regions of Thailand. METHODS: All patients diagnosed with cholangiocarcinoma between 2008 and 2013 were identified using the Nationwide Hospital Admission Data registry (n = 39421). Baseline characteristics, comorbidities and survival were abstracted. RESULTS: The annual incidence during the study period was stable in all regions. Most patients lived in the Northeast (62.8%), followed by the North (16.9%), Central (12.3%), Bangkok (5.4%), and South (n = 2.6%) regions (P < 0.0001). Significantly more cholangiocarcinoma patients had diabetes, cirrhosis, and chronic viral hepatitis B/C infection than non-cholangiocarcinoma participants (diabetes: 11.42% vs 5.28%; cirrhosis: 4.81% vs 0.92%; hepatitis B: 0.74% vs 0.12%; and hepatitis C: 0.50% vs 0.10%, P < 0.0001 for all, respectively). The overall 1-year mortality rate was 81.7%, with a stable trend over time. CONCLUSION: Diabetes and chronic liver diseases may be associated with cholangiocarcinoma in the Thai population.
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spelling pubmed-56564632017-11-01 Characteristics and outcomes of cholangiocarcinoma by region in Thailand: A nationwide study Chaiteerakij, Roongruedee Pan-ngum, Wirichada Poovorawan, Kittiyod Soonthornworasiri, Ngamphol Treeprasertsuk, Sombat Phaosawasdi, Kamthorn World J Gastroenterol Observational Study AIM: To identify the potential risk factors of cholangiocarcinoma, we determined the characteristics of cholangiocarcinoma patients among 5 different regions of Thailand. METHODS: All patients diagnosed with cholangiocarcinoma between 2008 and 2013 were identified using the Nationwide Hospital Admission Data registry (n = 39421). Baseline characteristics, comorbidities and survival were abstracted. RESULTS: The annual incidence during the study period was stable in all regions. Most patients lived in the Northeast (62.8%), followed by the North (16.9%), Central (12.3%), Bangkok (5.4%), and South (n = 2.6%) regions (P < 0.0001). Significantly more cholangiocarcinoma patients had diabetes, cirrhosis, and chronic viral hepatitis B/C infection than non-cholangiocarcinoma participants (diabetes: 11.42% vs 5.28%; cirrhosis: 4.81% vs 0.92%; hepatitis B: 0.74% vs 0.12%; and hepatitis C: 0.50% vs 0.10%, P < 0.0001 for all, respectively). The overall 1-year mortality rate was 81.7%, with a stable trend over time. CONCLUSION: Diabetes and chronic liver diseases may be associated with cholangiocarcinoma in the Thai population. Baishideng Publishing Group Inc 2017-10-21 2017-10-21 /pmc/articles/PMC5656463/ /pubmed/29093624 http://dx.doi.org/10.3748/wjg.v23.i39.7160 Text en ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Observational Study
Chaiteerakij, Roongruedee
Pan-ngum, Wirichada
Poovorawan, Kittiyod
Soonthornworasiri, Ngamphol
Treeprasertsuk, Sombat
Phaosawasdi, Kamthorn
Characteristics and outcomes of cholangiocarcinoma by region in Thailand: A nationwide study
title Characteristics and outcomes of cholangiocarcinoma by region in Thailand: A nationwide study
title_full Characteristics and outcomes of cholangiocarcinoma by region in Thailand: A nationwide study
title_fullStr Characteristics and outcomes of cholangiocarcinoma by region in Thailand: A nationwide study
title_full_unstemmed Characteristics and outcomes of cholangiocarcinoma by region in Thailand: A nationwide study
title_short Characteristics and outcomes of cholangiocarcinoma by region in Thailand: A nationwide study
title_sort characteristics and outcomes of cholangiocarcinoma by region in thailand: a nationwide study
topic Observational Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656463/
https://www.ncbi.nlm.nih.gov/pubmed/29093624
http://dx.doi.org/10.3748/wjg.v23.i39.7160
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