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CYP3A4 genotype is associated with sildenafil concentrations in patients with heart failure with preserved ejection fraction
Despite its established inter-individual variability, sildenafil has been the subject of only a few pharmacogenetic investigations, with limited data regarding the genetic modulators of its pharmacokinetics. We conducted a pharmacogenetic substudy of patients randomized to sildenafil (n = 85) in the...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656562/ https://www.ncbi.nlm.nih.gov/pubmed/28440343 http://dx.doi.org/10.1038/tpj.2017.8 |