PARP1-produced poly-ADP-ribose causes the PARP12 translocation to stress granules and impairment of Golgi complex functions

Poly-ADP-ribose-polymerases (PARPs) 1 and 2 are nuclear enzymes that catalyze the poly-ADP-ribosylation of nuclear proteins transferring poly-ADP-ribose (PAR) polymers to specific residues. PARPs and PAR intervene in diverse functions, including DNA repair in the nucleus and stress granule assembly...

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Detalles Bibliográficos
Autores principales: Catara, Giuliana, Grimaldi, Giovanna, Schembri, Laura, Spano, Daniela, Turacchio, Gabriele, Lo Monte, Matteo, Beccari, Andrea Rosario, Valente, Carmen, Corda, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656619/
https://www.ncbi.nlm.nih.gov/pubmed/29070863
http://dx.doi.org/10.1038/s41598-017-14156-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656619/
https://www.ncbi.nlm.nih.gov/pubmed/29070863
http://dx.doi.org/10.1038/s41598-017-14156-8

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