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MiR-193b regulates breast cancer cell migration and vasculogenic mimicry by targeting dimethylarginine dimethylaminohydrolase 1

Dimethylarginine dimethylaminohydrolase 1 (DDAH1) is responsible for metabolism of an endogenous inhibitor of nitric oxide synthase (NOS), asymmetric dimethylarginine (ADMA), which plays a key role in modulating angiogenesis. In addition to angiogenesis, tumours can establish a vascular network by f...

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Detalles Bibliográficos
Autores principales: Hulin, Julie-Ann, Tommasi, Sara, Elliot, David, Hu, Dong Gui, Lewis, Benjamin C., Mangoni, Arduino A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656623/
https://www.ncbi.nlm.nih.gov/pubmed/29070803
http://dx.doi.org/10.1038/s41598-017-14454-1