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Evaluation of the Effectiveness of Xanthine Oxidoreductase Inhibitors on Haemodialysis Patients using a Marginal Structural Model

A lower serum uric acid (UA) level has been associated with a higher mortality rate in haemodialysis patients. We investigated the long-term confounding factors of UA and mortality, and fitted a marginal structural model (MSM) based on the causal effect of xanthine oxidoreductase inhibitors (XORi)....

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Detalles Bibliográficos
Autores principales: Ishii, Takeo, Taguri, Masataka, Tamura, Kouichi, Oyama, Kunio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656650/
https://www.ncbi.nlm.nih.gov/pubmed/29070821
http://dx.doi.org/10.1038/s41598-017-13970-4