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Evaluation of Ga-DOTA-(D-Asp)(n) as bone imaging agents: D-aspartic acid peptides as carriers to bone
(67)Ga-DOTA-(L-Asp)(11) and (67)Ga-DOTA-(L-Asp)(14), which have been developed as bone imaging agents, showed a high accumulation in bone and a rapid blood clearance in mice. However, peptides composed of D-amino acids are more stable in vivo than those composed of their L-equivalents. In this study...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656653/ https://www.ncbi.nlm.nih.gov/pubmed/29070853 http://dx.doi.org/10.1038/s41598-017-14149-7 |