Cargando…
Structure based biophysical characterization of the PROPPIN Atg18 shows Atg18 oligomerization upon membrane binding
PROPPINs (β-propellers that bind polyphosphoinositides) are PtdIns3P and PtdIns(3,5)P(2) binding autophagy related proteins. They contain two phosphatidylinositolphosphate (PIP) binding sites and a conserved FRRG motif is essential for PIP binding. Here we present the 2.0 Å resolution crystal struct...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656675/ https://www.ncbi.nlm.nih.gov/pubmed/29070817 http://dx.doi.org/10.1038/s41598-017-14337-5 |