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Metabolic characterization of a CHO cell size increase phase in fed-batch cultures
Normally, the growth profile of a CHO cell fed-batch process can be divided into two main phases based on changes in cell concentration, being an exponential growth phase and a stationary (non-growth) phase. In this study, an additional phase is observed during which the cell division comes to a hal...
Autores principales: | Pan, Xiao, Dalm, Ciska, Wijffels, René H., Martens, Dirk E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656727/ https://www.ncbi.nlm.nih.gov/pubmed/28951949 http://dx.doi.org/10.1007/s00253-017-8531-y |
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