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Intestinal Fork Head Regulates Nutrient Absorption and Promotes Longevity
Reduced activity of nutrient-sensing signaling networks can extend organismal lifespan, yet the underlying biology remains unclear. We show that the anti-aging effects of rapamycin and reduced intestinal insulin/insulin growth factor (IGF) signaling (IIS) require the Drosophila FoxA transcription fa...
Autores principales: | Bolukbasi, Ekin, Khericha, Mobina, Regan, Jennifer C., Ivanov, Dobril K., Adcott, Jennifer, Dyson, Miranda C., Nespital, Tobias, Thornton, Janet M., Alic, Nazif, Partridge, Linda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656751/ https://www.ncbi.nlm.nih.gov/pubmed/29045833 http://dx.doi.org/10.1016/j.celrep.2017.09.042 |
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