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Time‐ and concentration‐dependent genomic responses of the rat airway to inhaled nickel sulfate

While insoluble nickel subsulfide (Ni(3)S(2)) was carcinogenic in the lung in a 2‐year rat bioassay, soluble nickel sulfate hexahydrate (NiSO(4*)6H(2)O) was not. To investigate whether differences in the cellular responses to these two nickel compounds could underlie their differential activities, w...

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Detalles Bibliográficos
Autores principales: Efremenko, A. Y., Campbell, J. L., Dodd, D. E., Oller, A. R., Clewell, H. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656831/
https://www.ncbi.nlm.nih.gov/pubmed/28862355
http://dx.doi.org/10.1002/em.22139